Proteins writing module PTE written summary 68

Proteins writing module PTE written summary 68

Proteins writing module PTE written summary 68

Read the passage below and summarize it using one sentence. Type your response in the box at the bottom of the screen. You have 10 minutes to finish this task. Your response  judged on the quality of your writing and on how well your response presents the key points in the passage.

Summarize Written text


About 120,000 types of protein molecule have yielded up their structures to science. That sounds a lot but it isn’t. The techniques such as X-Ray crystallography and nuclear magnetic resonance (NMR), which are used to elucidate such structures do not work on all proteins. Some types are hard to produce or purify in the volumes required. Others do not seem to crystallize at all – a prerequisite for probing them with X-rays. As a consequence, those structures that have been determined include representatives of less than a third of the 16,000 known protein families. Researchers can build reasonable computer models for around another third because the structures of these resemble ones already known. For the remainder, however, there is nothing to go on.

In addition to this lack of information about protein families, there is a lack of information about those from the species of most interest to researchers: Homo sapiens. Only a quarter of known protein structures are human. A majority of the rest come from bacteria. this paucity is a problem, for in proteins form and function are intimately related. A protein is a chain of smaller molecules, called amino acids, that is often hundreds or thousands of links long. By a process not well understood, this chain folds up, after it has been made, into a specific and complex three dimensional shape. That shape determines what the protein does: acting as a channel, say to admit a chemical into a cell ; or as an enzyme to accelerate a chemical reaction; or as a receptor, to receive chemical signals and pass them on to a cell’s molecular machinery.


As the current technologies that are used to elucidate the structure of proteins don’t work on all proteins, around one third of protein structure remain to be unknown and there is a lack of information on those species from where most protein structures are derived.


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